The production of 1,3-propanediol from mixtures of glycerol and glucose by a Klebsiella pneumoniae mutant deficient in carbon catabolite repression

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- 바이오플라스틱
  1. 고무
  2. 플라스틱
- 바이오정밀화학
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  2. 화학제품
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논문

The production of 1,3-propanediol from mixtures of glycerol and glucose by a Klebsiella pneumoniae mutant deficient in carbon catabolite repression

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Oh, B.R.; Hong, W.K.; Heo, S.Y.; Luo, L.H.; Kondo, A.; Seo, J.W.; Kim, C.H.

초록

In the present study, mutant strain of Klebsiella pneumoniae with deletion of the crr gene encoding EIIA<SUP>Glc</SUP> (a component of the glucose-specific phosphoenolpyruvate-dependent transferase system [PTS]) was prepared. This eliminated the ability of the strain to mediate carbon catabolite repression (CCR). Production of 1,3-propanediol (1,3-PD) from glycerol by the crr mutant strain was enhanced (compared to that of the parent) in the presence of glucose. Using molasses as a co-substrate of glycerol, the maximum yield of 1,3-PD was 60.4% greater (81.2g/l) than that obtained when glycerol was used alone, under optimum fermentation conditions.

발행연도

2013

발행기관

Elsevier Applied Science

ISSN

0960-8524

권

130

페이지

pp.719-724

DOI

10.1016/j.biortech.2012.12.076