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Evaluation of the Capparis Herbacea Willd's Chemistry, Antioxidant and Cytotoxic Activity

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바이오화학분류
    • 바이오플라스틱
      1. 고무
      2. 플라스틱
    • 바이오정밀화학
      1. 화학제품
    • 의료용 화학소재
      1. 식품첨가제
논문

Evaluation of the Capparis Herbacea Willd's Chemistry, Antioxidant and Cytotoxic Activity

학술지

Anti-inflammatory & anti-allergy agents in medicinal chemistry

저자명

Orynbassar Tleuberlina; Asem Mamurova; Zhanar Iskakova; Yelaman Aibuldinov; Ainagul Kolpek; Yeldar Kopishev; Gulbarshyn Satbaeva; Zhazira Mukazhanova; Meruyert Kurmanbayeva

초록

BACKGROUND: The Capparidaceae family includes the medicinal herb Capparis herbacea Willd. The aerial and underground parts of plant C.herbacea were studied for their chemical composition, antioxidant, and cytotoxic properties. METHODS: Using gas chromatography with mass spectrometric detection (7890A/5975C), 94 chemicals were identified in ethanol extract from leaves, roots, seeds, and stems of C. herbacea. Main components were (leaves) phytol 18.16%, hexanedioic acid, bis(2-ethylhexyl) ester 16.75%, vitamin E 11.95%, (roots) sucrose 13.94%, hexadecanoic acid, ethylester 22.80%, octadecanoic acid, ethylester 37.77%; (seeds) hexadecanoic acid, ethylester 13.96%, ethyl9.cis.,11.trans.-octadecadienoate 48.54%, bis(2-ethylhexyl) phthalate 9.77%; (stems) 1-propene-1,2,3-tricarboxylic acid, tributyl ester 42.69%, and tributylacetylcitrate 19.63%. Nine components were identified in the makeup of the C. herbacea sample's essential oil using the method of chromatography-mass spectrometry. RESULTS: The main components were (in%): T-cadinol (29.56), meta-cymene (16.12), pulegone (14.11), and σ-amorphene (12.26). Chloroform and methanol extracts of Capparis herbacia roots at concentrations of 1 mg/ml showed higher average antioxidant activity, while ethyl acetate root extract at concentrations of 0.75 and 1 mg/ml showed higher average antioxidant activity compared to gallic acid AOA. CONCLUSION: In addition, plant extracts have cytotoxic activity. Essential oils of leaves and stems, fruit and roots of Capparis herbacia plants exhibited cytotoxicity, all larvae died, and larval mortality was 96%.

발행연도

2023

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1 2023-12-11
2 2023-12-11

논문; 2023-01-01

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