BioChem - DOS

Reversible clustering of magnetic nanobiocatalysts for high-performance biocatalysis and easy catalyst recycling

Chemical communications : Chem comm

Ngo, Thao P. N.; Zhang, Wei; Wang, Wen; Li, Zhi

<P>Reversible clusters of nanobiocatalysts are developed <I>via</I> non-covalent interaction among enzyme-bound iron oxide magnetic nanoparticles. Dissociation of the clusters by shaking during biotransformation enables high catalytic performance, and re-clustering by stopping shaking after reaction allows for easy magnetic separation. The novel concept is demonstrated with alcohol dehydrogenase RDR for the enantioselective reduction of 7-methoxy-2-tetralone.</P><BR><BR><P>Graphic Abstract</P><P>Reversible nanobiocatalyst clusters are developed <I>via</I> non-covalent interaction among enzyme-bound iron oxide magnetic nanoparticles for efficient catalysis and easy separation.<BR><IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc30953j'><BR></P>

2012

The Royal Society of Chemistry

1359-7345

1364-548x

48

38

pp.4585-4587

10.1039/c2cc30953j

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART62235709