BioChem - DOS

Electroenzymatic process to overcome enzyme instabilities

Catalysis communications

Holtmann, D.; Krieg, T.; Getrey, L.; Schrader, J.

The versatile enzyme chloroperoxidase was used in a reaction system, based on a gas diffusion electrode, for enzymatic chlorinations. Due to an adjusted and continuous electro-generation of the co-substrate hydrogen peroxide a ttn up to 1,150,000 for the CPO was achieved. Space time yields were dependent on the electrochemically produced H<SUB>2</SUB>O<SUB>2</SUB> and reached up to 52gL<SUP>-1</SUP>d<SUP>-1</SUP>. The ratio of hydrogen peroxide production per added enzyme unit can be used as a dimensionless parameter for process characterization and a knowledge based process design.

2014

Elsevier

1566-7367

51

pp.82-85

10.1016/j.catcom.2014.03.033

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART68981638

Electrochemistry; Enzyme catalysis; Halogenation; Biotransformation