BioChem - DOS

Optimization of culture conditions of the thraustochytrid Aurantiochytrium sp. strain 18W-13a for squalene production

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

Nakazawa, Atsushi; Matsuura, Hiroshi; Kose, Ryoji; Kato, Syou; Honda, Daiske; Inouye, Isao; Kaya, Kunimitsu; Watanabe, Makoto M.

<P><B>Abstract</B></P><P>Optimum conditions of temperature, salinity and glucose concentration were investigated for squalene production of the strain of <I>Aurantiochytrium</I> sp. 18W-13a, with a high content of squalene. Squalene production by this strain was optimum at 25&deg;C, 25&ndash;50% seawater concentration and 2&ndash;6% glucose concentration. When this strain was grown in the optimum condition, the squalene content and production of approximately 171mg/g dry weight and 0.9g/L were much higher than that previously reported in thraustochytrids, plants and yeasts, respectively. Therefore, 18W-13a could be used as an alternative source of commercial squalene.</P>

2012

0960-8524

109

pp.287-291

10.1016/j.biortech.2011.09.127

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART58595371

Aurantiochytrium; Biomass; Hydrocarbon; Squalene; Thraustochytrid