BioChem - DOS

Sustainable Galactarate-Based Polymers: Multi-Enzymatic Production of Pectin-Derived Polyesters

Macromolecular rapid communications

Vastano, Marco; Pellis, Alessandro; Botelho Machado, Carla; Simister, Rachael; McQueen‐ Mason, Simon J.; Farmer, Thomas J.; Gomez, Leonardo D.

<P><B>Abstract</B></P><P>Large amounts of agricultural wastes are rich in pectins that, in many cases, disrupt the processing of food residues due to gelation. Despite pectins being a promising sustainable feedstock for bio&#8208;based chemical production, the current pathways to produce platform molecules from this polysaccharide are hazardous and entail the use of strong acids. The present work describes a sequence of biocatalyzed reactions that involves 1) the extraction of pectin from sugar beet pulp and enzymatic recovery of galacturonic acid (GalA), followed by 2) the enzymatic oxidation of the GalA aldehyde and the recovery of galactaric acid (GA), and 3) the biocatalyzed polycondensation of GA to obtain fully bio&#8208;based polyesters carrying lateral hydroxy functionalities. The acid&#8208;free pectin extraction is optimized using enzymes and microwave technology. The conditions for enzymatic oxidation of GalA allow the separation of the GA produced by a simple centrifugation step that leads to the enzyme&#8208;catalyzed polycondensation reactions.</P>

2019

1022-1336

1521-3927

40

22

pp.1900361

10.1002/marc.201900361

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART98287684

enzymatic oxidation; enzymatic synthesis; galactaric acid; pectin extraction; sugar&#x2010; derived polyesters;