Efficient production of L-lactic acid with high optical purity by alkaliphilic Bacillus sp. WL-S20

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  1. 고무
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- 바이오정밀화학
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  2. 화학제품
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  2. 건강보조식품
  3. 식품첨가제

논문

Efficient production of L-lactic acid with high optical purity by alkaliphilic Bacillus sp. WL-S20

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Meng, Y.; Xue, Y.; Yu, B.; Gao, C.; Ma, Y.

초록

Highly efficient polymer-grade l-lactic acid production was achieved by an alkaliphilic strain Bacillus sp. WL-S20 using inexpensive peanut meal as nitrogen source and sodium hydroxide as neutralizing agent. In multi-pulse fed-batch fermentation of Bacillus sp. WL-S20, a l-lactic acid concentration of 225g/l with a yield of 99.3% was obtained. In single-pulse fed-batch fermentation, a concentration of 180g/l was obtained with a yield of 98.6%. No d-isomers of lactic acid were detected. The production of a high concentration of optically pure l-lactic acid by alkaliphilic Bacillus sp. WL-S20, combined with a low-cost nutrient and environment-friendly NaOH-based process, represent a potentially novel way for l-lactic acid production at an industrial scale.

발행연도

2012

발행기관

Elsevier Applied Science

ISSN

0960-8524

권

116

페이지

pp.334-339

DOI

10.1016/j.biortech.2012.03.103