Bioproduction and extraction optimization of citric acid from Aspergillus niger by rotating drum type solid-state bioreactor

BioChem - DOS

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메타 데이터

바이오화학분류

- 바이오플라스틱
  1. 고무
  2. 플라스틱
- 바이오정밀화학
  1. 화학제품
- 화장품용 기능성소재
  1. 계면활성제⁄증점제

논문

Bioproduction and extraction optimization of citric acid from Aspergillus niger by rotating drum type solid-state bioreactor

학술지

Industrial crops and products

저자명

Dhillon, G.S.; Brar, S.K.; Kaur, S.; Verma, M.

초록

Solid-state citric acid fermentation was conducted in a 12-L rotating drum type bioreactor. The effect of inducers, ethanol and methanol were studied on citric acid bioproduction by Aspergillus niger NRRL 567 cultivated on apple pomace as a solid-substrate. Optimum conditions achieved for higher citric acid bioproduction (220.6+/-13.9g/kg dry solids, DS) were 3% (v/v) methanol, intermittent agitation of 1h after every 12h at 2rpm and 1vvm of aeration rate and 120h incubation time. The response surface optimization proved effective for higher citric acid extraction from fermented solid-substrate. Higher citric acid extraction of 294.19g/kg DS was achieved at optimum conditions: extraction time of 20min, agitation rate of 200rpm and extractant volume of 15ml by response surface methodology.

발행연도

2013

발행기관

Elsevier

ISSN

0926-6690

권

페이지

pp.78-84

DOI

10.1016/j.indcrop.2012.04.001

상세정보링크

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART63319886

주제어

[abr] SSF; solid state fermentation; Apple pomace; Aspergillus niger; Citric acid; Extraction optimization; Solid-state fermentation; [abr] ANOVA; analysis of variance; [abr] AP; apple pomace; [abr] CA; citric acid; [abr] CFUs; colony forming units; [abr] DS; dry substrate; [abr] EtOH; ethanol; [abr] gds; gram dry substrate; [abr] MeOH; methanol; [abr] OD; optical density; [abr] PDA; potato dextrose agar;