BioChem - DOS

A lipid membrane intercalating conjugated oligoelectrolyte enables electrode driven succinate production in Shewanella

Energy & environmental science

Thomas, Alexander W.; Garner, Logan E.; Nevin, Kelly P.; Woodard, Trevor L.; Franks, Ashley E.; Lovley, Derek R.; Sumner, James J.; Sund, Christian J.; Bazan, Guillermo C.

<P>An amphiphilic conjugated oligoelectrolyte (COE) that spontaneously intercalates into lipid membranes enables <I>Shewanella oneidensis</I> to use a graphite electrode as the sole electron donor for succinate production. Current consumed in a poised electrochemical system by <I>Shewanella</I> with micromolar concentrations of COE correlates well with the succinate produced <I>via</I> fumarate reduction as determined by HPLC analysis. Confocal microscopy confirms incorporation of the COE into the microbes on the electrode surface. This work presents a unique strategy to induce favorable bioelectronic interactions for the production of reduced microbial metabolites.</P><BR><BR><P>Graphic Abstract</P><P>A synthetic, lipid membrane intercalating molecule enables <I>Shewanella</I> to use a graphite electrode as the sole electron donor for production of succinate.<BR><IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3ee00071k'><BR></P>

2013

The Royal Society of Chemistry

1754-5692

1754-5706

6

6

pp.1761-1765

10.1039/c3ee00071k

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART66025731

https://works.bepress.com/cgi/viewcontent.cgi?article=1762&context=derek_lovley