Metabolic flux network analysis of fermentative hydrogen production: Using Clostridium tyrobutyricum as an example

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논문

Metabolic flux network analysis of fermentative hydrogen production: Using Clostridium tyrobutyricum as an example

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Cheng, H.H.; Whang, L.M.; Lin, C.A.; Liu, I.C.; Wu, C.W.

초록

This study applies metabolic flux network analysis (MFA) to evaluate the metabolic flux of fermentative hydrogen production (FHP) with the use of Clostridium tyrobutyricum fed with either glucose or lactate/acetate as substrates. The MFA results suggest that hydraulic retention time (HRT) presents significant impact on hydrogen production from glucose. At HRT between 4 and 18h, increase of HRT increased hydrogen production but decreased lactate production, while at HRT below 4h decrease of HRT increased hydrogen production but decreased lactate production. The flux for lactate, butyrate and acetate seemed to affect H<SUB>2</SUB> production, due presumably to their impacts on the balance of NADH, ferredoxin and ATP. It is suggested that the MFA can be a useful tool to provide valuable information for optimization and design of the fermentative hydrogen production process.

발행연도

2013

발행기관

Elsevier Applied Science

ISSN

0960-8524

권

141

페이지

pp.233-239

DOI

10.1016/j.biortech.2013.03.141