Seedpod extracts of Wrightia tinctoria shows significant anti-inflammatory effects in HepG2 and RAW-264.7cell lines

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- 바이오정밀화학
  1. 용매
  2. 화학제품
- 화장품용 기능성소재
  1. 계면활성제⁄증점제

논문

Seedpod extracts of Wrightia tinctoria shows significant anti-inflammatory effects in HepG2 and RAW-264.7cell lines

학술지

Natural product research

저자명

Karmakar, Eshani; Das, Prosenjit; Yatham, Priyanka; Kumar, Deepak; Mukhopadhyay, Satinath; Roy, Sib Sankar

초록

W. tinctoria, an Indian herb Indrajao, has significant therapeutic potential. While studies have highlighted the anti-inflammatory potential of the leaves and bark of this plant, similar efficacy of the seed-pods remains unexplored. We demonstrate significant anti-inflammatory effects of the hexane fraction (Fr-B) of ethyl acetate extract of the seedpods in reducing lipopolysaccharide and palmitate mediated inflammation in RAW264.7 macrophages and HepG2 cells. GC-MS and NMR profiling of Fr-B revealed the existence of hexadecanoic acid, ethyl hexadecanoate, 9,12-octadecanoic acid, 9,12,15-octadecatrienoic acid, 9,12,15-octadecatrienoic acid ethyl ester, ethyl linoleate and octadecanoic acid ethyl esters.

발행연도

2023

발행기관

Informa UK (TaylorFrancis)

ISSN

1478-6419

ISSN

1478-6427

권

호

페이지

pp.3158-3162