Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

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논문

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

학술지

Chem Inform

저자명

Mutti, Francesco G.; Knaus, Tanjy; Scrutton, Nigel S.; Breuer, Michael; Turner, Nicholas J.

초록

AbstractThe title amines are efficiently obtained from primary and secondary alcohols under environmentally benign reaction conditions using a combination of an alcohol dehydrogenase and an amine hydrogenase.

발행연도

2016

발행기관

WILEY‐VCH Verlag

ISSN

0931-7597

ISSN

1522-2667

권

호

페이지

pp.no-no

DOI

10.1126/science.aac9283

상세정보링크

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART74792373

원문파일

https://europepmc.org/articles/pmc4883652?pdf=render

주제어

amines (acyclic compounds); amines (benzene compounds); amination, N‐ alkylation, N‐ arylation; cascade reactions, domino reactions, tandem reactions; diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐ isomerism);