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Exploration and evaluation of antioxidant activity in isolated phenolics from Jasminum scandens (retz) vahl

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      2. 계면활성제⁄증점제
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논문

Exploration and evaluation of antioxidant activity in isolated phenolics from Jasminum scandens (retz) vahl

학술지

Natural product research

저자명

Afsin Malik; Faria Mannan Mithi; Sania Ashrafi; Muhammad Abdullah Al-Mansur; Monira Ahsan; Choudhury Mahmood Hasan; A T M Zafrul Azam

초록

Given the widespread and established use of Jasminum scandens (Retz) Vahl, a member of the Oleacea family, this study aimed to identify and characterise secondary metabolites derived from the plant, with the objective of evaluating their potential biological activities. Using chromatographic separations techniques based on molecular weight and polarity, various VLC fractions of the plant were purified. These fractions yielded seven compounds- 2-(4-hydroxyphenyl)-ethanol (1), 2-(4-hydroxy-3-methoxy-phenyl)-ethanol (2), 1-(4-hydroxy-3-methoxy-phenyl)-1,2,3-propanetriol (3), 1-(4-hydroxy-3,5-dimethoxy-phenyl)-1,2,3-propanetriol (4), lupeol (5), β-sitosterol (6), and methyl linoleate (7), which have never been previously reported in this plant. Out of the seven identified compounds, compounds 3 and 4 had the greatest capacity to scavenge free radicals with IC50 values of 3.81 µg/ml and 4.08 µg/ml, respectively when compared to the standard Butylated Hydroxy Toluene (BHT) with IC50 value of 6.54 µg/ml.

발행연도

2024

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1 2023-12-11

논문; 2024-04-03

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