BioChem - DOS

Kinetic modeling of sporulation and product formation in stationary phase by Bacillus coagulans RK-02 vis-a-vis other Bacilli

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

Das, S.; Sen, R.

A logistic kinetic model was derived and validated to characterize the dynamics of a sporogenous bacterium in stationary phase with respect to sporulation and product formation. The kinetic constants as determined using this model are particularly important for describing intrinsic properties of a sporogenous bacterial culture in stationary phase. Non-linear curve fitting of the experimental data into the mathematical model showed very good correlation with the predicted values for sporulation and lipase production by Bacillus coagulans RK-02 culture in minimal media. Model fitting of literature data of sporulation and product (protease and amylase) formation in the stationary phase by some other Bacilli and comparison of the results of model fitting with those of Bacillus coagulans helped validate the significance and robustness of the developed kinetic model.

2011

Elsevier Applied Science

0960-8524

102

20

pp.9659-9667

10.1016/j.biortech.2011.07.067

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART57412113

Kinetic modeling; Bacilli; Sporulation; Stationary phase product formation; Model validation