초록
<P>Peroxygenases are very promising catalysts for oxyfunctionalization reactions. Their practical applicability, however, is hampered by their sensitivity against the oxidant (H<SUB>2</SUB>O<SUB>2</SUB>), therefore necessitating in situ generation of H<SUB>2</SUB>O<SUB>2</SUB>. Here, we report a photoelectrochemical approach to provide peroxygenases with suitable amounts of H<SUB>2</SUB>O<SUB>2</SUB> while reducing the electrochemical overpotential needed for the reduction of molecular oxygen to H<SUB>2</SUB>O<SUB>2</SUB>. When tethered on single-walled carbon nanotubes (SWNTs) under illumination, flavins allowed for a marked anodic shift of the oxygen reduction potential in comparison to pristine SWNT and/or nonilluminated electrodes. This flavin-SWNT-based photoelectrochemical platform enabled peroxygenases-catalyzed, selective hydroxylation reactions.</P><P><B>Graphic Abstract</B><BR><IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/accacs/2017/accacs.2017.7.issue-3/acscatal.6b03453/production/images/medium/cs-2016-03453b_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cs6b03453'>ACS Electronic Supporting Info</A></P>