Biosynthesis of 2-amino-2,3-dimethylbutyramide by nitrile hydratase from a newly isolated cyanide-resistant strain of Rhodococcus qingshengii

BioChem - DOS

Search

메타 데이터

바이오화학분류

- 바이오플라스틱
  1. 플라스틱
  2. 기타
- 바이오정밀화학
  1. 화학제품
  2. 기타

논문

Biosynthesis of 2-amino-2,3-dimethylbutyramide by nitrile hydratase from a newly isolated cyanide-resistant strain of Rhodococcus qingshengii

학술지

Biotechnology letters. : a monthly journal for the rapid communication of results and developments in all aspects of biotechnology

저자명

Lin, Zhi-Jian; Zheng, Ren-Chao; Zheng, Yu-Guo; Shen, Yin-Chu

초록

<P>Cells of a new isolate of Rhodococcus qingshengii harboring nitrile hydratase converted 2-amino-2,3-dimethylbutyronitrile into 2-amino-2,3-dimethylbutyramide (ADBA). Cells also hydrated a broad range of substrates including saturated, unsaturated and cyclic aliphatic nitriles. The microorganism tolerated KCN and ADBA up to 5 mM and 40 g/l, respectively. At 10 C, ADBA reached 33.8 g/l (yield 84.5%) which was 2.5 times that at 30 C.</P>

발행연도

2011

발행기관

Springer-Verlag

ISSN

0141-5492

ISSN

1573-6776

권

호

페이지

pp.1809-1813