BioChem - DOS

Butyric acid production with Clostridium tyrobutyricum immobilised to PVA gel

Process biochemistry

Rebros, M.; Dolejs, I.; Stloukal, R.; Rosenberg, M.

Clostridium tyrobutyricum was entrapped into lens-shaped polyvinyl alcohol particles (LentiKats<SUP>&reg;</SUP>). Immobilised cells were propagated in series of repeated batches and reached average productivity of 1.74g/Lh and yield of 0.44g/g during 31 repetitions with glucose as an initial substrate, which was 5 times higher productivity compared with a free cell system under the same conditions. Immobilised cells were successfully applied for more than 71 repeated batches and demonstrated remarkable process stability. Application of immobilised cells to a continuous system resulted in 5.8 times higher productivity compared with free cells, with 6.8g/L of butyric acid and residual glucose of 5.8g/L.

2016

Elsevier Applied Science

1359-5113

51

6

pp.704-708

10.1016/j.procbio.2016.03.003

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART75517507

Clostridium tyrobutyricum; Butyric acid; Immobilisation; LentiKats^®