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Kinetic modeling for enzymatic hydrolysis of pretreated sugarcane straw

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논문

Kinetic modeling for enzymatic hydrolysis of pretreated sugarcane straw

학술지

Biochemical engineering journal

저자명

Angarita, J.D.; Souza, R.B.A.; Cruz, A.J.G.; Biscaia, E.C.; Secchi, A.R.

초록

A semimechanistic multi-reaction kinetic model was developed for modeling enzymatic hydrolysis of pretreated sugarcane straw (SCS) at high-solids concentration. The model, including: enzyme adsorption, xylose formation, end-product inhibition and substrate reactivity, was adjusted from a reference condition (enzyme concentration of 10 FPU/g-cellulose and solid loading of 15% w/v, dry basis). A simplified model was also proposed to overcome high parameter correlation and improve model fidelity. Predictive capacity of both simplified and original model was verified for different enzyme concentration (5-60 FPU/g-cellulose), solids loading (10 and 20 %) and end-product sugar inhibition (30 and 60g/L glucose, 10g/L cellobiose and 10g/L xylose). The glucose concentration was predicted with reasonable accuracy by the simplified model, even under critical conditions of sugar-inhibition. The model is able to describe batch saccharification of pretreated SCS at high-solids concentrations.

발행연도

2015

발행기관

Elsevier

ISSN

1369-703x

104

페이지

pp.10-19

주제어

Enzyme biocatalysis; Adsorption; Biokinetics; Modelling; Cellulose; Sugarcane straw

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1 2023-12-11
2 2023-12-11

논문; 2015-12-01

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