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Synthesis of 1,3-dioleoyl-2-arachidonoylglycerol-rich structured lipids by lipase-catalyzed acidolysis of microbial oil from Mortierella alpina

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바이오화학분류
    • 바이오정밀화학
      1. 화학제품
    • 화장품용 기능성소재
      1. 계면활성제⁄증점제
    • 의료용 화학소재
      1. 건강보조식품
      2. 식품첨가제
논문

Synthesis of 1,3-dioleoyl-2-arachidonoylglycerol-rich structured lipids by lipase-catalyzed acidolysis of microbial oil from Mortierella alpina

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Abed, Sherif M.; Zou, Xiaoqiang; Ali, Abdelmoneim H.; Jin, Qingzhe; Wang, Xingguo

초록

<P><B>Abstract</B></P> <P>Microbial oils (MOs) have gained widespread attention due to their functional lipids and health promoting properties. In this study, 1,3-dioleoyl-2-arachidonoylglycerol-rich structured lipids (SLs) were produced from MO and oleic acid (OA) via solvent-free acidolysis catalyzed by Lipozyme RM IM. Under the optimal conditions, the content of unsaturated fatty acids (UFAs) increased from 60.63 to 84.00%, while the saturated fatty acids (SFAs) content decreased from 39.37 to 16.00% at <I>sn</I>-1,3 positions in SLs. Compared with MO, arachidonic acid (ARA) content at the <I>sn</I>-2 position of SLs accounted for 49.71%, whereas OA was predominantly located at <I>sn</I>-1,3 positions (47.05%). Meanwhile, the most abundant triacylglycerol (TAG) species in SLs were (18:1-20:4-18:1), (20:4-20:4-18:1), (18:1-18:2-18:1), (18:1-18:2-18:0) and (24:0-20:4-18:1) with a relative content of 18.79%, 11.94%, 6.07%, 5.75% and 4.84%, respectively. Such novel SLs with improved functional properties enriched with UFAs are highly desirable and have the potential to be used in infant formula.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 1,3-Dioleoyl-2-arachidonoylglycerol-rich SLs were successfully produced. </LI> <LI> UFAs content at <I>sn</I>-1,3 positions of SLs increased from 60.63 to 84.00%. </LI> <LI> ARA content at the <I>sn</I>-2 position in SLs accounted for 49.71%. </LI> <LI> OA content at <I>sn</I>-1,3 positions of SLs increased from 2.35 to 47.05%. </LI> <LI> Such SLs enriched with UFAs have potential applications in the infant formula industry. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

발행연도

2017

발행기관

Elsevier

ISSN

0960-8524

243

페이지

pp.448-456

주제어

Arachidonic acid; Biocatalysis; Polyunsaturated fatty acids; Microbial oil; Structured lipids

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논문; 2017-11-01

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