초록
<P>Magnetic nanoparticles (MNPs) were covalently immobilized on the surface of <I>Acetobacter xylinus</I> and the location of the bacteria was controlled to manipulate bacterial bioactivation. The bacteria were positioned in the middle of an incubation tube by applying an external magnetic field, and the cellulose produced at the different metabolizing locations was characterized by X-ray diffraction, electron microscopy, and differential scanning calorimetry. To the best of our knowledge, this is the first experiment in which MNPs were employed in the control of cell metabolism.</P><P><B>Graphic Abstract</B><BR><IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2012/aamick.2012.4.issue-10/am301839c/production/images/medium/am-2012-01839c_0006.gif'></P>