Efficient calcium lactate production by fermentation coupled with crystallization-based in situ product removal

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바이오화학분류

- 바이오플라스틱
  1. 플라스틱
- 바이오정밀화학
  1. 기타
- 화장품용 기능성소재
  1. 계면활성제⁄증점제
- 의료용 화학소재
  1. 치료제
  2. 식품첨가제

논문

Efficient calcium lactate production by fermentation coupled with crystallization-based in situ product removal

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Xu, K.; Xu, P.

초록

Lactic acid is a platform chemical with various industrial applications, and its derivative, calcium lactate, is an important food additive. Fermentation coupled with in situ product removal (ISPR) can provide more outputs with high productivity. The method used in this study was based on calcium lactate crystallization. Three cycles of crystallization were performed during the fermentation course using a Bacillus coagulans strain H-1. As compared to fed-batch fermentation, this method showed 1.7 times higher average productivity considering seed culture, with 74.4% more l-lactic acid produced in the fermentation with ISPR. Thus, fermentation coupled with crystallization-based ISPR may be a biotechnological alternative that provides an efficient system for production of calcium lactate or lactic acid.

발행연도

2014

발행기관

Elsevier Applied Science

ISSN

0960-8524

권

163

페이지

pp.33-39

DOI

10.1016/j.biortech.2014.04.002