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Improved endoxylanase production and colony morphology of Aspergillus niger DSM 26641 by γ-ray induced mutagenesis

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논문

Improved endoxylanase production and colony morphology of Aspergillus niger DSM 26641 by γ-ray induced mutagenesis

학술지

Biochemical engineering journal

저자명

Ottenheim, Christoph; Werner, Katharina A.; Zimmermann, Wolfgang; Wu, Jin Chuan

초록

<P><B>Abstract</B></P> <P> <I>Aspergillus niger</I> DSM 26641 was exposed to <SUP>60</SUP>Co &gamma;-radiation to enhance the &beta;-1,4-endoxylanase activity, restrict colony growth and improve robustness of pellets. The first promising mutant obtained after &gamma;-radiation of the fungal spores at 50&ndash;2000Gy showed a restricted colony growth and an 82% enhancement in &beta;-1,4-endoxylanase activity. The mutant was subjected to a second round of &gamma;-radiation at 1400Gy generating a mutant with double the &beta;-1,4-endoxylanase activity compared to the native strain. The selected final mutant, deposited as <I>A. niger</I> DSM 28712, showed a maximal saccharification activity of 26Uml<SUP>&minus;1</SUP> on xylan based broth, 48Uml<SUP>&minus;1</SUP> on lignocellulose hydrolysate and 375Uml<SUP>&minus;1</SUP> on lignocellulose hydrolysate supplemented with yeast extract and mineral salts.</P> <P><B>Highlights</B></P> <P> <UL> <LI> &beta;-1,4-Endoxylanase activity of <I>Aspergillus niger</I> DSM 26641 was doubled by &gamma;-radiation. </LI> <LI> Restricted widespread filamentous growth on agar plates was observed. </LI> <LI> Miniaturization and pellet surface restriction favors biomass recycling. </LI> </UL> </P>

발행연도

2015

발행기관

Elsevier

ISSN

1369-703x

94

페이지

pp.9-14

주제어

Filamentous fungi; γ-radiation mutagenesis; Enzymes; Endoxylanase; Microbial growth; Optimization

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1 2023-12-11

논문; 2015-02-01

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