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One-pot chemo-enzymatic conversion of D-xylose to furfuralcohol by sequential dehydration with oxalic acid plus tin-based solid acid and bioreduction with whole-cells

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논문

One-pot chemo-enzymatic conversion of D-xylose to furfuralcohol by sequential dehydration with oxalic acid plus tin-based solid acid and bioreduction with whole-cells

학술지

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

저자명

Xue, Xin-Xia; Ma, Cui-Luan; Di, Jun-Hua; Huo, Xiao-Yu; He, Yu-Cai

초록

<P><B>Abstract</B></P> <P>In this study, organic acid could be used as co-catalyst for assisting solid acid SO<SUB>4</SUB> <SUP>2&minus;</SUP>/SnO<SUB>2</SUB>-argil to convert hemicellulose-derived <I>D</I>-xylose into furfural. The relationship between pKa of organic acid and turnover frequency (TOF) of co-catalysis with organic acid plus SO<SUB>4</SUB> <SUP>2&minus;</SUP>/SnO<SUB>2</SUB>-argil was explored on the conversion of <I>D-</I>xylose to furfural. Oxalic acid (pKa = 1.25) (0.35 wt%) was found to be the optimum co-catalyst for assisting SO<SUB>4</SUB> <SUP>2&minus;</SUP>/SnO<SUB>2</SUB>-argil (3.6 wt%) to synthesize furfural from <I>D-</I>xylose (20 g/L) at 180 &deg;C for 20 min, and the furfural yield and TOF could be obtained at 57.07% and 6.26 h<SUP>&minus;1</SUP>, respectively. Finally, the obtained furfural (107.6 mM) could be completely biotransformed to furfuralcohol by recombinant <I>Escherichia coli</I> CCZU-K14 whole-cells at 30 &deg;C and pH 6.5 in the presence of 1.5 mol glucose/mol furfural and 400 mM <I>D</I>-xylose. Clearly, this strategy shows high potential application for the effective synthesis of furfuralcohol from biomass-derived <I>D</I>-xylose.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Relationship between pKa of organic acid and TOF of co-catalysis was explored. </LI> <LI> Oxalic acid (pKa = 1.25) gave the maximum TOF value (6.26 h<SUP>&minus;1</SUP>). </LI> <LI> Furfural was synthesized from <I>D-</I>xylose with oxalic acid plus SO<SUB>4</SUB> <SUP>2&minus;</SUP>/SnO<SUB>2</SUB>-argil. </LI> <LI> High furfural yield (50.8%) from <I>D-</I>xylose (50 g/L) was achieved. </LI> <LI> An effective approach for one-pot synthesis of FOL from <I>D</I>-xylose was demonstrated. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

발행연도

2018

발행기관

Elsevier

ISSN

0960-8524

268

페이지

pp.292-299

주제어

D-Xylose; Furfuralcohol; SO4 2&#x2212; /SnO2-argil; Oxalic acid; Escherichia coli CCZU-K14;

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1 2023-12-11

논문; 2018-11-01

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