BioChem - DOS

Rational engineering of Candida antarctica lipase B for selective monoacylation of diols

Chemical communications : Chem comm

Hamberg, Anders; Maurer, Steffen; Hult, Karl

<P>The enzyme <I>Candida antarctica</I> lipase B was subjected to site directed mutagenesis suggested by molecular modelling. The selectivity for the enzyme increased towards a range of diols over their corresponding monoesters as an effect of the mutations.</P><BR><BR><P>Graphic Abstract</P><P>The enzyme <I>Candida antarctica</I> lipase B was subjected to site directed mutagenesis suggested by molecular modelling.<BR><IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc34684b'><BR></P>

2012

The Royal Society of Chemistry

1359-7345

1364-548x

48

80

pp.10013-10015

10.1039/c2cc34684b

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART64082976