BioChem - DOS

Effects of Exogenous Erythropoietin on Rabbit (Oryctolagus cuniculus) Hematological and Biochemical Parameters

Comparative medicine

Levine, Jessica K; Seixas, Josilene Nascimento; Ritter, Jana M; Liew, Amanda Y; Tansey, Cassandra M

<P>Rabbits can develop anemia due to serial phlebotomy or secondary to induced disease states. This study evaluated the effects of a single injection and three consecutive injections of erythropoietin in rabbits at 150 IU/kg and 1,000 IU/kg in order to determine whether these dosages produce a sustained increase in hematocrit. Analysis of CBC and chemistry parameters showed significant elevation in hematocrit one week after administration of 1,000 IU/kg erythropoietin for three consecutive days. These results indicate that this dosage regimen can increase hematocrit in apparently healthy, nonanemic rabbits for one week.</P>

2023

American Association for Laboratory Animal Science

1532-0820

73

6

pp.439-445

10.30802/aalas-cm-22-000107

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART128367694