초록
<P><B>Abstract</B></P> <P>The dynamics of the membrane fatty acid composition of a succinic acid-producing bacterium, <I>Anaerobiospirillum succiniciproducens</I>, was studied using continuous and batch cultures. In both batch and chemostat continuous culture conditions, <I>A. succiniciproducens</I> grown on glucose or glycerol responded to acid stress by lowering the content of saturated fatty acids (SFAs) and increasing the content of unsaturated fatty acids (UFAs). Notably, <I>A. succiniciproducens</I> elongated C16:0 (SFA) and converted it to C18:1 (UFA) in the pH-uncontrolled culture, which is a common bacterial adaptation strategy to combat acid stress. Interestingly, <I>A. succiniciproducens</I> did not exhibit a significant increase in cyclic FA content, which is another common strategy to cope with acidic conditions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fatty acid change of succinic acid-producing <I>A. succiniciproducens</I> was studied. </LI> <LI> The cells responded to acid stress by lowering saturated fatty acid content. </LI> <LI> The cells responded to acid stress by increasing unsaturated fatty acid content. </LI> <LI> The cells did not increase cyclic FA content in response to acid stress. </LI> </UL> </P>