BioChem - DOS

Scale-up and kinetic modeling for bioethanol production

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

Imamoglu, E.; Sukan, F.V.

Bioethanol was produced from acidic hydrolysate of rice hulls using recombinant Escherichia coli KO11. Two different issues (scale-up and kinetic modeling) were evaluated simultaneously and concomitantly for bioethanol production. During the step-wise scale-up process from 100mL shaken flask to 10L stirred-tank bioreactor, the constant Reynolds number and the constant impeller tip speed were evaluated as scale-up methodologies under laboratory conditions. It was determined that the volumetric bioethanol productivity was 88% higher in 10L bioreactor in comparison to the value of 0.21gL<SUP>-1</SUP>h<SUP>-1</SUP> in shaken flask. The modified Monod and Luedeking-Piret models provided an accurate approach for the modeling of the experimental data. Ethanol concentration reached the maximum level of 29.03g/L, which was 5% higher than the value of model prediction in 10L bioreactor. The findings of this research could contribute to the industrial scale productions especially from lignocellulosic raw materials.

2013

Elsevier Applied Science

0960-8524

144

pp.311-320

10.1016/j.biortech.2013.06.118

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART66561811

Bioethanol production; Scale-up; Shaken flask; Stirred-tank bioreactors; Kinetic modeling