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Alkaline Protease from Nocardiopsis arvandica UTMC 1492 Isolated from Saline Soil with the Ability to Produce Bioactive Protein Hydrolysate

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논문

Alkaline Protease from Nocardiopsis arvandica UTMC 1492 Isolated from Saline Soil with the Ability to Produce Bioactive Protein Hydrolysate

학술지

Industrial biotechnology

저자명

Mohammadipanah, Fatemeh; Ghelichkhani, Farid; Khajeh, Khosro; Hamedi, Javad

초록

<P><B>Abstract</B></P><P><I>Proteases constitute more than half of the industrial enzymes sales and among them, alkaline proteases are of high industrial impact. The strain identified as</I> Nocardiopsis <I>UTMC 1492 was isolated from the rhizosphere of</I> Salsola <I>sp. from saline soils. Growth at high concentration of salt and high protease activity introduced the</I> Nocardiopsis <I>UTMC 1492 as a valuable candidate for scale up fermentation and purification of its protease. In spite of 100% identity in 16S rRNA gene of</I> Nocardiopsis <I>sp. UTMC 1492 to</I> N. arvandica, <I>cultural and physiological differences suggest that microenvironment adaptation of a single strain can lead to the significant change in the behavior of the microorganism. Enzyme purification was carried out by two-step Q-sepharose fast protein liquid chromatography (FPLC)</I><I>with pH 11.0 and 8.0, followed by ammonium sulfate precipitation. This enzyme was &sim;30 kDa. The partially purified enzyme showed optimum activity at 60&deg;C and pH 9.0. This enzyme showed antioxidant producing peptones by hydrolyzing proteins extracted from rapeseed, which demonstrated its potential capability in food and feed industries.</I></P>

발행연도

2018

발행기관

Mary Ann Liebert, Inc.

ISSN

1550-9087

14

1

페이지

pp.54-60

주제어

Rare actinomycete; Nocardiopsis; antioxidant peptone hydrolyzates; nutraceutical; rapeseed

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1 2023-12-11

논문; 2018-12-31

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