BioChem - DOS

A membrane-integrated fermentation reactor system: its effects in reducing the amount of sub-raw materials for D-lactic acid continuous fermentation by Sporolactobacillus laevolacticus

Bioscience, biotechnology, and biochemistry

MIMITSUKA, Takashi; NA, Kyungsu; MORITA, Ken; SAWAI, Hideki; MINEGISHI, Shinichi; HENMI, Masahiro; YAMADA, Katsushige; SHIMIZU, Sakayu; YONEHARA, Tetsu

<P>Continuous fermentation by retaining cells with a membrane-integrated fermentation reactor (MFR) system was found to reduce the amount of supplied sub-raw material. If the amount of sub-raw material can be reduced, continuous fermentation with the MFR system should become a more attractive process for industrialization, due to decreased material costs and loads during the refinement process. Our findings indicate that the production rate decreased when the amount of the sub-raw material was reduced in batch fermentation, but did not decrease during continuous fermentation with <I>Sporolactobacillus laevolacticus</I>. Moreover, continuous fermentation with a reduced amount of sub-raw material resulted in a productivity of 11.2 g/L/h over 800 h. In addition, the index of industrial process applicability used in the MFR system increased by 6.3-fold as compared with the conventional membrane-based fermentation reactor previously reported, suggesting a potential for the industrialization of this <SMALL>D</SMALL>-lactic acid continuous fermentation process.</P>

2012

Japan Society for Bioscience, Biotechnology, and Agrochemistry

0916-8451

1347-6947

76

1

pp.67-72

10.1271/bbb.110499

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART58435405

continuous fermentation; Sporolactobacillus laevolacticus; membrane; lactic acid