초록
Efficient l-lactic acid production from xylose was achieved using a pyruvate decarboxylase-deficient Candida utilis strain expressing an l-lactate dehydrogenase, an NADH-preferring mutated xylose reductase (XR), a xylitol dehydrogenase and a xylulokinase. The recombinant strain showed 53% increased l-lactic acid production compared with the reference strain expressing native XR (NADPH-preferring).