초록
<P><B>ABSTRACT</B></P><P><B>BACKGROUND</B></P><P>The cost of 1,3‐propanediol (1,3‐PD) microbial production depends very much on the separation of 1,3‐PD from the fermentation broth. This work develops a salting‐out process separating 1,3‐PD from aqueous solutions. The salting‐out effects of K<SUB>2</SUB>CO<SUB>3</SUB>, K<SUB>3</SUB>PO<SUB>4</SUB>, and K<SUB>4</SUB>P<SUB>2</SUB>O<SUB>7</SUB> on the liquid–liquid phase equilibria for different aqueous solutions of 1,3‐PD were investigated at 298.15 K.</P><P><B>RESULTS</B></P><P>The distribution coefficient and selectivity coefficient of 1,3‐PD increased significantly with increase of the initial salt concentration in the salting‐out systems. Increasing the initial 1,3‐PD concentration in the aqueous solution improved the distribution coefficient and selectivity coefficient of 1,3‐PD, resulting in higher recovery of 1,3‐PD.</P><P><B>CONCLUSION</B></P><P>The solubility of 1,3‐PD in the aqueous phase was mainly determined by the salt species and its concentration. The initial 1,3‐PD concentration in the aqueous solution had a negligible effect on the solubility of 1,3‐PD in the aqueous phase, which showed a linear relation with the molality of salt in the aqueous phase. Moreover, the solubility of 1,3‐PD in the organic phase or the aqueous phase could be predicted by the initial salt concentration. © 2016 Society of Chemical Industry</P>