BioChem - DOS

Succinic Acid Production in Fed-Batch Fermentation of Anaerobiospirillum succiniciproducens Using Glycerol as Carbon Source

Chemical engineering & technology

Bretz, Karlheinz

<P><B>Abstract</B></P><P>Considering glycerol as an inexpensive alternative carbon source, the optimal glycerol concentration for succinic acid production with <I>Anaerobiospirillum succiniciproducens</I> was identified in shake&#8208;flask trials. The addition of a defined amount of glucose improved the growth and succinic acid productivity significantly. In fed&#8208;batch processes with glycerol as sole substrate, a maximum succinic acid concentration and product substrate yield were obtained. The addition of glucose led to a 2.5&#8208;fold increased succinic acid concentration whereas the product substrate yield remained nearly constant.</P>

2015

WILEY&#x2010;VCH Verlag

0930-7516

1521-4125

38

9

pp.1659-1664

10.1002/ceat.201500015

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART73022349

Anaerobiospirillum succiniciproducens, Fed&#x2010; batch fermentation; Glycerol; Succinic acid production;