One-pot one-step deracemization of amines using ω-transaminases

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논문

One-pot one-step deracemization of amines using ω-transaminases

학술지

Chemical communications : Chem comm

저자명

Shin, Giyoung; Mathew, Sam; Shon, Minsu; Kim, Byung-Gee; Yun, Hyungdon

초록

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion. Graphic AbstractIn this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3cc43348j'>

발행연도

2013

발행기관

The Royal Society of Chemistry

ISSN

1359-7345

ISSN

1364-548x

권

호

페이지

pp.8629-8631