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Effect of carbon pulsing on the redox household of Lactobacillus diolivorans in order to enhance 1,3-propanediol production

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논문

Effect of carbon pulsing on the redox household of Lactobacillus diolivorans in order to enhance 1,3-propanediol production

학술지

New biotechnology

저자명

Lindlbauer, K.A.; Marx, H.; Sauer, M.

초록

This study investigates potential limitations of 1,3-propanediol formation by Lactobacillus diolivorans. Particular focus is given to enhanced glycerol utilization as well as the elimination of by-product formation. The key aspect is a modulation of the redox household by process engineering through the application of carbon pulses. A shift in the product pattern of C3 products was achieved, improving the ratio of 1,3-propanediol versus 3-hydroxypropionic acid up to a level of 20:1. Moreover, in combination with alternative feeding strategies this ratio was enhanced up to 45:1 and the maximum observed productivity of 1,3-propanediol could be significantly increased to 1.7g/Lh.

발행연도

2017

발행기관

Elsevier

ISSN

1871-6784

34

페이지

pp.32-39

주제어

1,3-propanediol; 3-hydroxypropionic acid; Glycerol utilization; Lactobacillus diolivorans

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논문; 2017-01-01

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