초록
<P><B>Abstract</B></P><P><I>Enterobacter aerogenes</I> is one of the most widely-studied model strains for fermentative hydrogen production. To improve the hydrogen yield of <I>E. aerogenes</I>, the bioengineering on a biomolecular level and metabolic network level is of importance. In this review, the fermentative technology of <I>E. aerogenes</I> for hydrogen production will be first briefly summarized. And then the bioengineering of <I>E. aerogenes</I> for the improvement of hydrogen yield will be thoroughly reviewed, including the anaerobic metabolic networks for hydrogen evolution in <I>E. aerogenes</I>, metabolic engineering for improving hydrogen production in <I>E. aerogenes</I> and mixed culture of <I>E. aerogenes</I> with other hydrogen-producing bacteria to enhance the overall yield in anaerobic cultivation. Finally, a perspective on <I>E. aerogenes</I> as a hydrogen producer including systems bioengineering approach for improving the hydrogen yield and application of the engineered <I>E. aerogenes</I> in mixed culture will be presented.</P>