Anaerobic obligatory xylitol production in Escherichia coli strains devoid of native fermentation pathways

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논문

Anaerobic obligatory xylitol production in Escherichia coli strains devoid of native fermentation pathways

학술지

Applied and environmental microbiology

저자명

Akinterinwa, Olubolaji; Cirino, Patrick C.

초록

ABSTRACT Anaerobic glucose oxidation was coupled to xylose reduction in a nonfermentative Escherichia coli strain expressing NADPH-dependent xylose reductase. Xylitol production serves as the primary means of NAD(P) + regeneration, as glucose is converted primarily to acetate and CO 2 . The membrane-bound transhydrogenase PntAB is required to achieve the maximum theoretical yield of four moles of xylitol per mole of glucose consumed.

발행연도

2011

발행기관

American Society for Microbiology

ISSN

0099-2240

ISSN

1098-5336

권

호

페이지

pp.706-709