BioChem - DOS

Inhibition effect of secondary metabolites accumulated in a pervaporation membrane bioreactor on ethanol fermentation of Saccharomyces cerevisiae

Bioresource technology : biomass, bioenergy, biowastes, conversion technologies, biotransformations, production technologies

Fan, S.; Xiao, Z.; Tang, X.; Chen, C.; Zhang, Y.; Deng, Q.; Yao, P.; Li, W.

The secondary metabolites accumulated in a pervaporation membrane bioreactor during ethanol fermentation were mostly composed of acetic acid, lactic acid, propionic acid, citric acid, succinic acid and glycerol. The inhibition effect of these compounds at a broad concentration range was studied through ethanol fermentation by Saccharomyces cerevisiae. An increasing concentration of the secondary metabolites led to longer lag time and a reduction of cell growth. The specific cell growth rate, cell yield, ethanol productivity were only 0.061h<SUP>-1</SUP>, 0.024, 0.47gL<SUP>-1</SUP>h<SUP>-1</SUP> respectively, when the medium contained 3.12g of acetic acid, 10.23g of lactic acid, 2.72g of propionic acid, 1.35g of citric acid, 2.26g of succinic acid and 49.25g of glycerol per liter (a concentration level in pervaporation membrane bioreactor at later fermentation period). By increasing pH of the medium to 6.0-8.0, the inhibition of these secondary metabolites could be greatly relieved.

2014

Elsevier Applied Science

0960-8524

162

pp.8-13

10.1016/j.biortech.2014.03.140

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART69045467

Ethanol fermentation; Secondary metabolites; Inhibition effect; Pervaporation membrane bioreactor; Saccharomyces cerevisiae