BioChem - DOS

Biocatalytic resolution of enantiomeric mixtures of 1-aminoethanephosphonic acid

Molecules a journal of synthetic chemistry and natural product chemistry

Brzeziń ska-Rodak, Małgorzata; Klimek-Ochab, Magdalena; Ż ymań czyk-Duda, Ewa; Kafarski, Paweł

<P>Several fungal strains, namely <I>Bauveria bassiana, Cuninghamella echinulata, Aspergillus fumigatus, Penicillium crustosum</I> and <I>Cladosporium herbarum</I>, were used as biocatalysts to resolve racemic mixtures of 1-aminoethanephosphonic acid using L/D amino acid oxidase activity. The course of reaction was analyzed by <SUP>31</SUP>P-NMR in the presence of cyclodextrin used as chiral discriminating agent. The best result (42% e.e of <I>R</I>-isomer) was obtained with a strain of <I>Cuninghamella echinulata.</I></P>

2011

MDPI

cc-by

1420-3049

16

7

pp.5896-5904

10.3390/molecules16075896

http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=05787966&target=NART&cn=NART73672326

https://www.mdpi.com/1420-3049/16/7/5896/pdf?version=1403113148

aminophosphonic acid; fungi; resolution of racemic mixture